Automatic extraction of 3d dynamic left ventricle model from 2d rotational angiocardiogram

  • Authors:
  • Mingqing Chen;Yefeng Zheng;Kerstin Mueller;Christopher Rohkohl;Guenter Lauritsch;Jan Boese;Gareth Funka-Lea;Joachim Hornegger;Dorin Comaniciu

  • Affiliations:
  • Image Analytics and Informatics, Siemens Corporate Research, Princeton, NJ;Image Analytics and Informatics, Siemens Corporate Research, Princeton, NJ;Healthcare Sector, Siemens AG, Forchheim and Pattern Recognition Lab, University Erlangen-Nuremberg, Germany;Healthcare Sector, Siemens AG, Forchheim, Germany;Healthcare Sector, Siemens AG, Forchheim, Germany;Healthcare Sector, Siemens AG, Forchheim, Germany;Image Analytics and Informatics, Siemens Corporate Research, Princeton, NJ;Pattern Recognition Lab, University Erlangen-Nuremberg, Germany;Image Analytics and Informatics, Siemens Corporate Research, Princeton, NJ

  • Venue:
  • MICCAI'11 Proceedings of the 14th international conference on Medical image computing and computer-assisted intervention - Volume Part III
  • Year:
  • 2011

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Abstract

In this paper, we propose an automatic method to directly extract 3D dynamic left ventricle (LV) model from sparse 2D rotational angiocardiogram (each cardiac phase contains only five projections). The extracted dynamic model provides quantitative cardiac function for analysis. The overlay of the model onto 2D real-time fluoroscopic images provides valuable visual guidance during cardiac intervention. Though containing severe cardiac motion artifacts, an ungated CT reconstruction is used in our approach to extract a rough static LV model. The initialized LV model is projected onto each 2D projection image. The silhouette of the projected mesh is deformed to match the boundary of LV blood pool. The deformation vectors of the silhouette are back-projected to 3D space and used as anchor points for thin plate spline (TPS) interpolation of other mesh points. The proposed method is validated on 12 synthesized datasets. The extracted 3D LV meshes match the ground truth quite well with a mean point-to-mesh error of 0.51±0.11mm. The preliminary experiments on two real datasets (included a patient and a pig) show promising results too.