High performance informatics for pandemic preparedness
Proceedings of the Winter Simulation Conference
Interaction-based HPC modeling of social, biological, and economic contagions over large networks
Proceedings of the Winter Simulation Conference
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Large scale realistic simulations of malware on mobile wireless networks have recently become an increasingly important application of high-performance computing. We propose EpiCure - an individual-based, scalable high performance computing oriented modeling environment to study malware propagation over realistic mobile networks. It is designed specifically to work on commodity cluster architectures. EpiCure runs extremely fast for realistic instances that involve: (i) large time-varying networks consisting of millions of heterogeneous individuals with time varying interaction neighborhoods, (ii) dynamic interactions between disease propagation, device behavior, and the exogenous interventions, and (iii) large number of replicated runs necessary for statistically sound estimates about the stochastic epidemic evolution. We find that EpiCure runs several orders of magnitude faster than another comparable simulation tool while delivering similar results. Beyond simple compute speed, EpiCure has been designed so that analysts can easily represent a range of interventions leading to improved human productivity and ease of use. This is an increasingly important metric in high performance computing. We illustrate EpiCure using three case studies that bring out the novel features of EpiCure.