A contour-oriented approach to shape analysis
A contour-oriented approach to shape analysis
IEEE Transactions on Pattern Analysis and Machine Intelligence
Shape measures for content based image retrieval: a comparison
Information Processing and Management: an International Journal
A Framework for Discrete Integral Transformations I—The Pseudopolar Fourier Transform
SIAM Journal on Scientific Computing
A Framework for Discrete Integral Transformations II—The 2D Discrete Radon Transform
SIAM Journal on Scientific Computing
Fourier Preprocessing for Hand Print Character Recognition
IEEE Transactions on Computers
Fourier Descriptors for Plane Closed Curves
IEEE Transactions on Computers
Image processing techniques for assessing contractility in isolated adult cardiac myocytes
Journal of Biomedical Imaging
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We describe a computational framework for the quantitative assessment of contractile responses of isolated neonatal cardiac myocytes. To the best of our knowledge, this is the first report on a practical and accessible method for the assessment of contractility in neonatal cardiocytes. The proposed methodology is comprised of digital video recording of the contracting cell, signal preparation, representation by polar Fourier descriptors, and contractility assessment. The different processing stages are variants of mathematically sound and computationally robust algorithms very well established in the scientific community. The described computational approach provides a comprehensive assessment of the neonatal cardiac myocyte contraction without the need of elaborate instrumentation. The versatility of the methodology allows it to be employed in determiningmyocyte contractility almost simultaneously with the acquisition of the Ca2+ transient and other correlates of cell contraction. The proposed methodology can be utilized to evaluate changes in contractile behavior resulting from drug intervention, disease models, transgeneity, or other common applications of neonatal cardiocytes.