Biclustering of Expression Data
Proceedings of the Eighth International Conference on Intelligent Systems for Molecular Biology
Biclustering Algorithms for Biological Data Analysis: A Survey
IEEE/ACM Transactions on Computational Biology and Bioinformatics (TCBB)
Shifting and scaling patterns from gene expression data
Bioinformatics
Tensor Decompositions and Applications
SIAM Review
Approximation algorithms for tensor clustering
ALT'09 Proceedings of the 20th international conference on Algorithmic learning theory
Bioinformatics
A unified adaptive co-identification framework for high-d expression data
PRIB'12 Proceedings of the 7th IAPR international conference on Pattern Recognition in Bioinformatics
Hi-index | 0.00 |
A new framework is proposed to study the co-clustering of gene expression data. This framework is based on a generic tensor optimization model and an optimization method termed Maximum Block Improvement (MBI) recently developed in [3]. Not only can this framework be applied for co-clustering gene expression data with genes expressed at different conditions represented in 2D matrices, but it can also be readily applied for co-clustering more complex high-dimensional gene expression data with genes expressed at different tissues, different development stages, different time points, different stimulations, etc. Moreover, the new framework is so flexible that it poses no difficulty at all to incorporate a variety of clustering quality measurements. In this paper, we demonstrate the effectiveness of this new approach by providing the details of one specific implementation of the algorithm, and presenting the experimental testing on microarray gene expression datasets. Our results show that the new algorithm is very efficient and it performs well for identifying patterns in gene expression datasets.