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Medical technological advances have been instrumental in improving the physical health of many individuals over the past 50 years. However, the impact that a patient's care experience has on their emotional health has just begun to be explored. Using quantitative, qualitative, and design research methods, I am researching stress, anxiety, and perceptions of care in cancer patients undergoing radiation therapy. This 3-tiered methodological approach allows me to create a holistic understanding of the patient experience. Based upon insights gained from this data, I am implementing design interventions within this environment to evaluate their ability to improve the patient experience.