Detection of spots in 2-d electrophoresis gels by symmetry features

Authors:
Martin Persson;Josef Bigun
Affiliations:
School of Information Science, Computer and Electrical Engineering, Halmstad University, Halmstad, Sweden;School of Information Science, Computer and Electrical Engineering, Halmstad University, Halmstad, Sweden
Venue:
ICAPR'05 Proceedings of the Third international conference on Advances in Pattern Recognition - Volume Part I
Year:
2005

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Abstract

We have implemented an algorithm for detection and segmentation of protein spots in 2-D gel electrophoresis images using symmetry derivative features computed using low level image processing operations. The implementation was compared with a previously published Watershed segmentation and a commercial software. Our algorithm was found to yield segmentation results that were either better than or comparable to the other solutions while having fewer free parameters and a low computational cost.