A biological text retrieval system based on background knowledge and user feedback

  • Authors:
  • Meng Hu;Jiong Yang

  • Affiliations:
  • EECS, Case Western Reserve University, Cleveland, OH;EECS, Case Western Reserve University, Cleveland, OH

  • Venue:
  • VDMB'06 Proceedings of the First international conference on Data Mining and Bioinformatics
  • Year:
  • 2006

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Abstract

Efficiently finding the most relevant publications in large corpus is an important research topic in information retrieval. The number of biological literatures grows exponentially in various publication databases. The objective of this paper is to quickly identify useful publications from a large number of biological documents. In this paper, we introduce a new iterative search paradigm that integrates biomedical background knowledge in organizing the results returned by search engines and utilizes user feedbacks in pruning irrelevant documents by document classification. A new term weighting strategy based on Gene Ontology is proposed to represent biomedical literatures. A prototype text retrieval system is built on this iterative search approach. Experimental results on MEDLINE abstracts and different keyword inputs show that the system can filter a large number of irrelevant documents in a reasonable time while keeping most of the useful documents. The results also show that the system is robust against different inputs and parameter settings.