Automatic Quantification of MS Lesions in 3D MRI Brain Data Sets: Validation of INSECT
MICCAI '98 Proceedings of the First International Conference on Medical Image Computing and Computer-Assisted Intervention
An Extensible MRI Simulator for Post-Processing Evaluation
VBC '96 Proceedings of the 4th International Conference on Visualization in Biomedical Computing
Anatomical standardization of the human brain in euclidean 3-space and on the cortical 2-manifold
Anatomical standardization of the human brain in euclidean 3-space and on the cortical 2-manifold
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Cortical surface reconstruction is important for functional brain mapping and morphometric analysis of the brain cortex. Several methods have been developed for the faithful reconstruction of surface models which describe the true cortical surface in both geometry and topology. However there has been no explicit method for the quantitative evaluation of the whole-cortical-surface models. In this study, we present a novel phantom-based evaluation method of the cortical surface reconstruction algorithm and quantitatively validated the local morphometric accuracy of CLASP which is one of the well-established reconstruction methods. The evaluation included local geometrical accuracy and performance of cortical thickness measure. The validation study revealed that there were some underestimations of cortical thickness measure using CLASP in the ventral and sulcal areas of the cortex and overestimations in the gyral areas and inferior temporal lobe. This study could present a generic metric for the quantitative evaluation of cortical surface reconstruction algorithm.