Active shape models—their training and application
Computer Vision and Image Understanding
IEEE Transactions on Pattern Analysis and Machine Intelligence
Tetrahedral Mesh Modeling of Density Data for Anatomical Atlases and Intensity-Based Registration
MICCAI '00 Proceedings of the Third International Conference on Medical Image Computing and Computer-Assisted Intervention
Iconic feature based nonrigid registration: the PASHA algorithm
Computer Vision and Image Understanding - Special issue on nonrigid image registration
Statistical atlases of bone anatomy: construction, iterative improvement and validation
MICCAI'07 Proceedings of the 10th international conference on Medical image computing and computer-assisted intervention - Volume Part I
Computer Methods and Programs in Biomedicine
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We present a framework for statistical finite element analysis combining shape and material properties, and allowing performing statistical statements of biomechanical performance across a given population. In this paper, we focus on the design of orthopaedic implants that fit a maximum percentage of the target population, both in terms of geometry and biomechanical stability. CT scans of the bone under consideration are registered non-rigidly to obtain correspondences in position and intensity between them. A statistical model of shape and intensity (bone density) is computed by means of principal component analysis. Afterwards, finite element analysis (FEA) is performed to analyse the biomechanical performance of the bones. Realistic forces are applied on the bones and the resulting displacement and bone stress distribution are calculated. The mechanical behaviour of different PCA bone instances is compared.