Plaque type, plaque burden, and wall shear stress relation in coronary arteries assessed by x-ray angiography and intravascular ultrasound: a qualitative study

  • Authors:
  • Simone Balocco;Carlo Gatta;Xavier Carrillo;Josepa Mauri;Petia Radeva

  • Affiliations:
  • Universitat de Barcelona, Barcelona, Bellaterra, Spain;Universitat de Barcelona, Barcelona, Bellaterra, Spain;Hospital universitari Germans Trias i Pujol Badalona, Spain;Hospital universitari Germans Trias i Pujol Badalona, Spain;Universitat de Barcelona, Barcelona, Spain

  • Venue:
  • Proceedings of the 4th International Symposium on Applied Sciences in Biomedical and Communication Technologies
  • Year:
  • 2011

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Abstract

In this paper, we present a complete framework that automatically provides fluid-dynamic and plaque analysis from IVUS and Angiographic sequences. Such framework is used to analyze, in three coronary arteries, the relation between wall shear stress with type and amount of plaque. Preliminary qualitative results show an inverse relation between the wall shear stress and the plaque burden, which is confirmed by the fact that the plaque growth is higher on the wall having concave curvature. Regarding the plaque type it was observed that regions having low shear stress are predominantly fibro-lipidic while the heavy calcifications are in general located in areas of the vessel having high WSS.