Molecular learning of wDNF formulae

  • Authors:
  • Byoung-Tak Zhang;Ha-Young Jang

  • Affiliations:
  • Biointelligence Laboratory, Seoul National University, Seoul, Korea;Biointelligence Laboratory, Seoul National University, Seoul, Korea

  • Venue:
  • DNA'05 Proceedings of the 11th international conference on DNA Computing
  • Year:
  • 2005

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Abstract

We introduce a class of generalized DNF formulae called wDNF or weighted disjunctive normal form, and present a molecular algorithm that learns a wDNF formula from training examples. Realized in DNA molecules, the wDNF machines have a natural probabilistic semantics, allowing for their application beyond the pure Boolean logical structure of the standard DNF to real-life problems with uncertainty. The potential of the molecular wDNF machines is evaluated on real-life genomics data in simulation. Our empirical results suggest the possibility of building error-resilient molecular computers that are able to learn from data, potentially from wet DNA data.