MR diffusion-based inference of a fiber bundle model from a population of subjects

  • Authors:
  • V. El Kouby;Y. Cointepas;C. Poupon;D. Rivière;N. Golestani;J. -B. Poline;D. Le Bihan;J. -F. Mangin

  • Affiliations:
  • Service Hospitalier Frédéric Joliot, CEA, Orsay, France;Service Hospitalier Frédéric Joliot, CEA, Orsay, France;Service Hospitalier Frédéric Joliot, CEA, Orsay, France;Service Hospitalier Frédéric Joliot, CEA, Orsay, France;Service Hospitalier Frédéric Joliot, CEA, Orsay, France;Institut Fédératif de Recherche 49 (Imagerie Neurofonctionnelle), Paris;Service Hospitalier Frédéric Joliot, CEA, Orsay, France;Service Hospitalier Frédéric Joliot, CEA, Orsay, France

  • Venue:
  • MICCAI'05 Proceedings of the 8th international conference on Medical Image Computing and Computer-Assisted Intervention - Volume Part I
  • Year:
  • 2005

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Abstract

This paper proposes a method to infer a high level model of the white matter organization from a population of subjects using MR diffusion imaging. This method takes as input for each subject a set of trajectories stemming from any tracking algorithm. Then the inference results from two nested clustering stages. The first clustering converts each individual set of trajectories into a set of bundles supposed to represent large white matter pathways. The second clustering matches these bundles across subjects in order to provide a list of candidates for the bundle model. The method is applied on a population of eleven subjects and leads to the inference of 17 such candidates.