Inductive logic programming: issues, results and the challenge of learning language in logic
Artificial Intelligence - Special issue on applications of artificial intelligence
S.cerevisiae complex function prediction with modular multi-relational framework
IEA/AIE'10 Proceedings of the 23rd international conference on Industrial engineering and other applications of applied intelligent systems - Volume Part III
MMRF for Proteome annotation applied to human protein disease prediction
ILP'10 Proceedings of the 20th international conference on Inductive logic programming
DS'06 Proceedings of the 9th international conference on Discovery Science
A new relational Tri-training system with adaptive data editing for inductive logic programming
Knowledge-Based Systems
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Protein-protein interactions play an important role in many fundamental biological processes. Computational approaches for predicting protein-protein interactions are essential to infer the functions of unknown proteins, and to validate the results obtained of experimental methods on protein-protein interactions. We have developed an approach using Inductive Logic Programming (ILP) for protein-protein interaction prediction by exploiting multiple genomic data including protein-protein interaction data, SWISS-PROT database, cell cycle expression data, Gene Ontology, and InterPro database. The proposed approach demonstrates a promising result in terms of obtaining high sensitivity/specificity and comprehensible rules that are useful for predicting novel protein-protein interactions. We have also applied our method to a number of protein-protein interaction data, demonstrating an improvement on the expression profile reliability (EPR) index.