ANN-Based system for sorting spike waveforms employing refractory periods

  • Authors:
  • Thomas Hermle;Martin Bogdan;Cornelius Schwarz;Wolfgang Rosenstiel

  • Affiliations:
  • Wilhelm-Schickard-Institut für Informatik, Technische Informatik, Universität Tübingen, Tübingen, Germany;Wilhelm-Schickard-Institut für Informatik, Technische Informatik, Universität Tübingen, Tübingen, Germany;Hertie-Institut für klinische Hirnforschung, Kognitive Neurologie, Universitätsklinik Tübingen, Tübingen, Germany;Wilhelm-Schickard-Institut für Informatik, Technische Informatik, Universität Tübingen, Tübingen, Germany

  • Venue:
  • ICANN'05 Proceedings of the 15th international conference on Artificial Neural Networks: biological Inspirations - Volume Part I
  • Year:
  • 2005

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Abstract

We describe a modification of a growing grid neural net for the purpose of sorting neuronal spike waveforms from extracellular recordings in the central nervous system. We make use of the fact, that real neurons exhibit a refractory period after firing an action potential during which they can not create a new one. This information is utilized to control the growth process of a growing grid, which we use to classify spike waveforms. The new algorithm is an alternative to a standard self-organizing map used in our previously published spike sorting system. Using simulated data, we show that this modification can further improve the accuracy in sorting neuronal spike waveforms.