The budgeted maximum coverage problem
Information Processing Letters
prefuse: a toolkit for interactive information visualization
Proceedings of the SIGCHI Conference on Human Factors in Computing Systems
CSV: visualizing and mining cohesive subgraphs
Proceedings of the 2008 ACM SIGMOD international conference on Management of data
| Hi-index | 0.00 |
Despite recent progress in high-throughput experimental studies, systems level visualization and analysis of large protein interaction networks (PPI) remains a challenging task, given its scale and high-dimensionality. Specifically, techniques that automatically abstract and summarize PPIs at multiple resolutions to provide high level views of its functional landscape are still lacking. In this demonstration, we present a novel data-driven and generic system called FUSE (Functional Summary Generator) that generates functional maps of a PPI at different levels of organization, from broad process-process level interactions to in-depth complex-complex level interactions. By simultaneously evaluating interaction and annotation data, FUSE abstracts higher-order interaction maps by reducing the details of the underlying PPI to form a functional summary graph of interconnected functional clusters. We demonstrate various innovative features of FUSE which aid users to visualize these summaries in a user-friendly manner and navigate through complex PPIs.