Numerical simulation of radio frequency ablation with state dependent material parameters in three space dimensions

  • Authors:
  • Tim Kröger;Inga Altrogge;Tobias Preusser;Philippe L. Pereira;Diethard Schmidt;Andreas Weihusen;Heinz-Otto Peitgen

  • Affiliations:
  • CeVis – Center for Complex Systems and Visualization, University of Bremen, Germany;CeVis – Center for Complex Systems and Visualization, University of Bremen, Germany;CeVis – Center for Complex Systems and Visualization, University of Bremen, Germany;Dept. of Diagnostic Radiology, Eberhard Karls University, Tübingen, Germany;Dept. of Diagnostic Radiology, Eberhard Karls University, Tübingen, Germany;MeVis – Center for Medical Diagnostic Systems and Visualization, Bremen, Germany;CeVis – Center for Complex Systems and Visualization, University of Bremen, Germany

  • Venue:
  • MICCAI'06 Proceedings of the 9th international conference on Medical Image Computing and Computer-Assisted Intervention - Volume Part II
  • Year:
  • 2006

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Abstract

We present a model for the numerical simulation of radio frequency (RF) ablation of tumors with mono- or bipolar probes. This model includes the electrostatic equation and a variant of the well-known bio-heat transfer equation for the distribution of the electric potential and the induced heat. The equations are nonlinearly coupled by material parameters that change with temperature, dehydration and damage of the tissue. A fixed point iteration scheme for the nonlinear model and the spatial discretization with finite elements are presented. Moreover, we incorporate the effect of evaporation of water from the cells at high temperatures using a predictor-corrector like approach. The comparison of the approach to a real ablation concludes the paper.