Semantic web technologies for interpreting DNA microarray analyses: the MEAT system

Authors:
Khaled Khelif;Rose Dieng-Kuntz;Pascal Barbry
Affiliations:
INRIA Sophia Antipolis, Sophia Antipolis, France;INRIA Sophia Antipolis, Sophia Antipolis, France;IPMC, Sophia Antipolis, France
Venue:
WISE'05 Proceedings of the 6th international conference on Web Information Systems Engineering
Year:
2005

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Abstract

This paper describes MEAT (Memory of Experiments for the Analysis of Transcriptomes), a project aiming at supporting biologists working on DNA microarrays. We provide methodological and software support to build an experiment memory for this domain. Our approach, based on Semantic Web Technologies, is relying on formalized ontologies and semantic annotations of scientific articles and other knowledge sources. It can probably be extended to other massive analyses of biological events (as provided by proteomics, metabolomics...).