MicroCASim: an automata network simulator applied to the competition between microparasites and host immune response

  • Authors:

  • Luciana B. Furlan;Henrique F. Gagliardi;Fabrício A. B. da Silva;Ivan T. Pisa;Domingos Alves

  • Affiliations:

  • Departamento de Informática em Saúde (DIS), UNIFESP, São Paulo, SP, Brazil;Laboratório de Computação Científica Aplicada à Saúde Coletiva (LCCASC), UNISANTOS, Santos, SP, Brazil;Programa de Mestrado em Informática, UNISANTOS, Santos, SP, Brazil;Departamento de Informática em Saúde (DIS), UNIFESP, São Paulo, SP, Brazil;Laboratório de Computação Científica Aplicada à Saúde Coletiva (LCCASC), UNISANTOS, Santos, SP, Brazil

  • Venue:
  • ICCS'06 Proceedings of the 6th international conference on Computational Science - Volume Part I
  • Year:
  • 2006

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Abstract

In this work we had developed an alternative model framework to study the concept of immunological memory by proposing as a simplified model for the interaction dynamics between a population of pathogens and the immunological system. The model is based on a probabilistic cellular automata which allows relatively easy inclusion of some of the real immunological systems in a transparently biological manner. The resulting virtual laboratory is called Microscopic Cellular Automata Simulator (MicroCASim), a software whose basic idea is to create a tool to assist the visualization of the interaction dynamics of these entities in silico.