Writing by methylation proposed for aqueous computing
Where mathematics, computer science, linguistics and biology meet
Aqueous Solutions of Algorithmic Problems: Emphasizing Knights on a 3 x 3
DNA 7 Revised Papers from the 7th International Workshop on DNA-Based Computers: DNA Computing
Aqueous computing: a survey with an invitation to participate
Journal of Computer Science and Technology
DNA13'07 Proceedings of the 13th international conference on DNA computing
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The MethyLogic method performs flexible and reversible modification of DNA in order to establish the logical value of true or false for a set of clauses. It combines both the biological meaning and experimental procedure with the logical implementation of the basic Boolean operators: OR, AND, and NOT. The original feature of methylation logic, MethyLogic, is the use of the reversibility of DNA methylation of cytosine and adenine. Logic variables can be negated by reversing the DNA methylation status. We introduce four implementation scenarios: three of them use methyl-sensitive restriction enzymes and the fourth uses methyl-binding proteins. Encoding can use either single or double-stranded DNA. In addition, we show how to solve a three variable SAT problem and how to implement a logic circuit.