International Journal of Computer Vision
Medical image segmentation using topologically adaptable surfaces
CVRMed-MRCAS '97 Proceedings of the First Joint Conference on Computer Vision, Virtual Reality and Robotics in Medicine and Medial Robotics and Computer-Assisted Surgery
Fast Extraction of Tubular and Tree 3D Surfaces with Front Propagation Methods
ICPR '02 Proceedings of the 16 th International Conference on Pattern Recognition (ICPR'02) Volume 1 - Volume 1
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We present a fast algorithm for automatic extraction of a 3D cerebrovascular system from time-of-flight (TOF) magnetic resonance angiography (MRA) data. Blood vessels are separated from background tissues (fat, bones, or grey and white brain matter) by voxel-wise classification based on precise approximation of a multi-modal empirical marginal intensity distribution of the TOF-MRA data. The approximation involves a linear combination of discrete Gaussians (LCDG) with alternating signs, and we modify the conventional Expectation-Maximization (EM) algorithm to deal with the LCDG. To validate the accuracy of our algorithm, a special 3D geometrical phantom motivated by statistical analysis of the MRA-TOF data is designed. Experiments with both the phantom and 50 real data sets confirm high accuracy of the proposed approach.