Local search for the maximum parsimony problem

  • Authors:
  • Adrien Goëffon;Jean-Michel Richer;Jin-Kao Hao

  • Affiliations:
  • LERIA, University of Angers, Angers Cedex 01, France;LERIA, University of Angers, Angers Cedex 01, France;LERIA, University of Angers, Angers Cedex 01, France

  • Venue:
  • ICNC'05 Proceedings of the First international conference on Advances in Natural Computation - Volume Part III
  • Year:
  • 2005

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Abstract

Four local search algorithms are investigated for the phylogenetic tree reconstruction problem under the Maximum Parsimony criterion. A new subtree swapping neighborhood is introduced and studied in combination with an effective array-based tree representation. Computational results are shown on a set of randomly generated benchmark instances as well as on 8 real problems (sequences of phytopathogen γ-proteobacteria) and compared with two references from the literature.