Classification of chromosome sequences with entropy kernel and LKPLS algorithm

  • Authors:
  • Zhenqiu Liu;Dechang Chen

  • Affiliations:
  • Department of Statistics, The Ohio State University, Columbus, OH;Preventive Medicine and Biometrics, Uniformed Services University of the Health Sciences, Bethesda, MD

  • Venue:
  • ICIC'05 Proceedings of the 2005 international conference on Advances in Intelligent Computing - Volume Part I
  • Year:
  • 2005

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Abstract

Kernel methods such as support vector machines have been used extensively for various classification tasks. In this paper, we describe an entropy based string kernel and a novel logistic kernel partial least square algorithm for classification of sequential data. Our experiments with a human chromosome dataset show that the new kernel can be computed efficiently and the algorithm leads to a high accuracy especially for the unbalanced training data.