Elements of information theory
Elements of information theory
Methodological review: Computerized analysis of pigmented skin lesions: A review
Artificial Intelligence in Medicine
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In the diagnosis of malignant melanoma, a skin cancer, the degree of irregularity along the skin lesion border is an important diagnostic factor. This paper presents a new measure of border irregularity based on conditional entropy. The measure was tested on 98 skin lesions of which 16 were malignant melanoma. The ROC analysis showed that the measure is 70% sensitive and 84% specific in discriminating the malignant and benign lesions. These results compare favourably with other measures and indicate that conditional entropy captures some distinguishing features in the boundary of malignant lesions.