A new approach to sequence representation of proteins in bioinformatics

  • Authors:
  • Angel F. Kuri-Morales;Martha R. Ortiz-Posadas

  • Affiliations:
  • Departamento de Computación, Instituto Tecnológico Autónomo de México;Laboratorio de Informática Médica. Departamento de Ingeniería Eléctrica, Universidad Autónoma Metropolitana Iztapalapa

  • Venue:
  • MICAI'05 Proceedings of the 4th Mexican international conference on Advances in Artificial Intelligence
  • Year:
  • 2005

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Abstract

A method to represent arbitrary sequences (strings) is discussed. We emphasize the application of the method to the analysis of the similarity of sets of proteins expressed as sequences of amino acids. We define a pattern of arbitrary structure called a metasymbol. An implementation of a detailed representation is discussed. We show that a protein may be expressed as a collection of metasymbols in a way such that the underlying structural similarities are easier to identify.