The state of the art in locally distributed Web-server systems
ACM Computing Surveys (CSUR)
Simulation of Dynamic Grid Replication Strategies in OptorSim
GRID '02 Proceedings of the Third International Workshop on Grid Computing
Data Management in an International Data Grid Project
GRID '00 Proceedings of the First IEEE/ACM International Workshop on Grid Computing
Decoupling Computation and Data Scheduling in Distributed Data-Intensive Applications
HPDC '02 Proceedings of the 11th IEEE International Symposium on High Performance Distributed Computing
Grid Computing: Making the Global Infrastructure a Reality
Grid Computing: Making the Global Infrastructure a Reality
Data Replication Strategies in Grid Environments
ICA3PP '02 Proceedings of the Fifth International Conference on Algorithms and Architectures for Parallel Processing
Evaluating Scheduling and Replica Optimisation Strategies in OptorSim
GRID '03 Proceedings of the 4th International Workshop on Grid Computing
A survey of Web cache replacement strategies
ACM Computing Surveys (CSUR)
Guest editorial: special issue on scalable web services and architecture
Journal of Parallel and Distributed Computing - Scalable web services and architecture
Stork: Making Data Placement a First Class Citizen in the Grid
ICDCS '04 Proceedings of the 24th International Conference on Distributed Computing Systems (ICDCS'04)
The Grid 2: Blueprint for a New Computing Infrastructure
The Grid 2: Blueprint for a New Computing Infrastructure
A survey of life sciences applications on the grid
New Generation Computing - Grid systems for life sciences
Parallel Computing - Special issue: High-performance parallel bio-computing
Integration of scheduling and replication in data grids
HiPC'04 Proceedings of the 11th international conference on High Performance Computing
Grid Deployment of Legacy Bioinformatics Applications with Transparent Data Access
GRID '06 Proceedings of the 7th IEEE/ACM International Conference on Grid Computing
Web services interface to run protein sequence tools on grid, testcase of protein sequence alignment
ISBMDA'06 Proceedings of the 7th international conference on Biological and Medical Data Analysis
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One of the first motivations of using grids comes from applications managing large data sets like for example in High Energy Physic or Life Sciences. To improve the global throughput of software environments, replicas are usually put at wisely selected sites. Moreover, computation requests have to be scheduled among the available resources. To get the best performance, scheduling and data replication have to be tightly coupled which is not always the case in existing approaches. This paper presents an algorithm that combines data management and scheduling at the same time using a steady-state approach. Our theoretical results are validated using simulation and logs from a large life science application (ACI GRID GriPPS). The PattInProt application searches sites and signatures of proteins into databanks of protein sequences.