Poster: hybrid parallelization of a realistic heart model

Authors:
Dorian Krause;Mark Potse;Thomas Dickopf;Rolf Krause;Angelo Auricchio;Frits Prinzen
Affiliations:
University of Lugano, Lugano, Switzerland;Maastricht University, Maastricht, Netherlands;University of Lugano, Lugano, Switzerland;University of Lugano, Lugano, Switzerland;Fondazione Cardiocentro Ticino, Lugano, Switzerland;Maastricht University, Maastricht, Netherlands
Venue:
Proceedings of the 2011 companion on High Performance Computing Networking, Storage and Analysis Companion
Year:
2011

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Abstract

Heart failure is a major health problem, not only for the number of people affected (about five million in Europe alone) but also because of the direct and indirect costs for its treatment. A thorough understanding of the complex electrical activation system that triggers the mechanical contraction is a prerequisite for developing effective treatment strategies. Full-heart simulations are an indispensable tool to study the effect of molecular-level or tissue-level changes on clinical measurements [2]. Cardiac electrical activity originates in the millions of ion channels and pumps that are located in the outer membrane of each cardiac muscle cell. We denote the macroscopic ionic current density by Iion.