A SVR-Based multiple modeling algorithm for antibiotic fermentation process using FCM

  • Authors:
  • Yaofeng Xue;Jingqi Yuan

  • Affiliations:
  • Department of Automation, Shanghai Jiao Tong University, Shanghai, China;Department of Automation, Shanghai Jiao Tong University, Shanghai, China

  • Venue:
  • ISNN'05 Proceedings of the Second international conference on Advances in Neural Networks - Volume Part III
  • Year:
  • 2005

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Abstract

A multiple modeling algorithm for antibiotic fermentation process based on fuzzy c-means (FCM) and support vector regression (SVR) is proposed. By analyzing the features of antibiotic fermentation, the mechanism of multiple modeling of the bioprocess is presented. Using FCM clustering method, the bioprocess is classified into several work states and sub-models. Then, taking advantage of the generalization properties of SVR, the multiple model of bioprocess is established and the proposed algorithm is described. Experimental data of industrial penicillin production is used to validate the model.