The after-hyperpolarization amplitude and the rise time constant of IPSC affect the synchronization properties of networks of inhibitory interneurons

  • Authors:
  • Angelo Di Garbo;Alessandro Panarese;Michele Barbi;Santi Chillemi

  • Affiliations:
  • Istituto di Biofisica CNR, Sezione di Pisa, Pisa, Italy;Istituto di Biofisica CNR, Sezione di Pisa, Pisa, Italy;Istituto di Biofisica CNR, Sezione di Pisa, Pisa, Italy;Istituto di Biofisica CNR, Sezione di Pisa, Pisa, Italy

  • Venue:
  • IWANN'05 Proceedings of the 8th international conference on Artificial Neural Networks: computational Intelligence and Bioinspired Systems
  • Year:
  • 2005

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Abstract

The Fast Spiking (FS) interneurons are coupled by both electrical and inhibitory synapses and experimental findings suggest that they operate as a clockwork affecting the processing of neural information. At present, it is not known which is the functional role of electrical synapses in a network of inhibitory interneurons. In our contribution, by using a single compartment biophysical model of an FS cell, we determine the parameter values leading to the emergence of synchronous regimes in a network of FS interneurons coupled by chemical and electrical synapses. We also compare our results with those recently obtained for a pair of coupled Integrate & Fire neural models [1].