A simple computational cell: Coupling boolean gene and protein networks

Authors:
Larry Bull
Affiliations:
University of the West of England
Venue:
Artificial Life
Year:
2012

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Abstract

This article presents an abstract, tunable model containing two of the principal information-processing features of cells and explores its use with simulated evolution. The random Boolean model of genetic regulatory networks is extended to include a protein interaction network. The underlying behavior of the resulting two coupled dynamical networks is investigated before their evolvability is explored using a version of the NK model of fitness landscapes.