Fundamentals of statistical signal processing: estimation theory
Fundamentals of statistical signal processing: estimation theory
Using HyTech to Synthesize Control Parameters for a Steam Boiler
Formal Methods for Industrial Applications, Specifying and Programming the Steam Boiler Control (the book grow out of a Dagstuhl Seminar, June 1995).
CAV '91 Proceedings of the 3rd International Workshop on Computer Aided Verification
BUSpec: A framework for generation of verification aids for standard bus protocol specifications
Integration, the VLSI Journal
Robustness analysis and tuning of synthetic gene networks
Bioinformatics
A Counterexample-Guided Approach to Parameter Synthesis for Linear Hybrid Automata
HSCC '08 Proceedings of the 11th international workshop on Hybrid Systems: Computation and Control
Parameter Synthesis for Piecewise Affine Systems from Temporal Logic Specifications
HSCC '08 Proceedings of the 11th international workshop on Hybrid Systems: Computation and Control
A Model Checking Approach to the Parameter Estimation of Biochemical Pathways
CMSB '08 Proceedings of the 6th International Conference on Computational Methods in Systems Biology
Parameter Synthesis for Hybrid Systems with an Application to Simulink Models
HSCC '09 Proceedings of the 12th International Conference on Hybrid Systems: Computation and Control
Parameter Synthesis in Nonlinear Dynamical Systems: Application to Systems Biology
RECOMB 2'09 Proceedings of the 13th Annual International Conference on Research in Computational Molecular Biology
Inverse bifurcation analysis of a model for the mammalian G1/S regulatory module
BIRD'07 Proceedings of the 1st international conference on Bioinformatics research and development
Parameter Scanning by Parallel Model Checking with Applications in Systems Biology
PDMC-HIBI '10 Proceedings of the 2010 Ninth International Workshop on Parallel and Distributed Methods in Verification, and Second International Workshop on High Performance Computational Systems Biology
Time Series Dependent Analysis of Unparametrized Thomas Networks
IEEE/ACM Transactions on Computational Biology and Bioinformatics (TCBB)
Parameter identification and model ranking of thomas networks
CMSB'12 Proceedings of the 10th international conference on Computational Methods in Systems Biology
Temporal Logics for Phylogenetic Analysis via Model Checking
IEEE/ACM Transactions on Computational Biology and Bioinformatics (TCBB)
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An important problem in current computational systems biology is to analyze models of biological systems dynamics under parameter uncertainty. This paper presents a novel algorithm for parameter synthesis based on parallel model checking. The algorithm is conceptually universal with respect to the modeling approach employed. We introduce the algorithm, show its scalability, and examine its applicability on several biological models.