Applications of level set methods in computational biophysics

  • Authors:
  • Emmanuel Maitre;Thomas Milcent;Georges-Henri Cottet;Annie Raoult;Yves Usson

  • Affiliations:
  • Université de Grenoble and CNRS, Laboratoire Jean Kuntzmann, France;Université de Grenoble and CNRS, Laboratoire Jean Kuntzmann, France;Université de Grenoble and CNRS, Laboratoire Jean Kuntzmann, France;Université Paris Descartes and CNRS, Laboratoire MAP5, France;Université de Grenoble and CNRS, Laboratoire TIMC, France

  • Venue:
  • Mathematical and Computer Modelling: An International Journal
  • Year:
  • 2009

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Abstract

We describe in this paper two applications of Eulerian level set methods to fluid-structure problems arising in biophysics. The first one is concerned with three-dimensional equilibrium shapes of phospholipidic vesicles. This is a complex problem, which can be recast as the minimization of the curvature energy of an immersed elastic membrane, under a constant area constraint. The second deals with isolated cardiomyocyte contraction. This problem corresponds to a generic incompressible fluid-structure coupling between an elastic body and a fluid. By the choice of these two quite different situations, we aim to bring evidence that Eulerian methods provide efficient and flexible computational tools in biophysics applications.