On the Convergence of Pattern Search Algorithms
SIAM Journal on Optimization
Pattern Search Algorithms for Bound Constrained Minimization
SIAM Journal on Optimization
Pattern Search Methods for Linearly Constrained Minimization
SIAM Journal on Optimization
Engineering Applications of Artificial Intelligence
Shape optimization for tumor location
Computers & Mathematics with Applications
Preface: Mathematical methods and modelling of biophysical phenomena
Mathematical and Computer Modelling: An International Journal
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In non-invasive thermal diagnostics, accurate correlations between the thermal image on skin surface and interior human physiology are often desired, which require general solutions for the bioheat equation. In this study an estimation methodology is presented to determine unknown thermophysical or geometrical parameters of a tumor region using the temperature profile on the skin surface that may be obtained by infrared thermography. To solve these inverse problems a second order finite difference scheme was implemented to solve the bioheat Pennes equation with mixed boundary conditions in two and three dimensions. Then, the Pattern Search algorithm was used to estimate the different parameters by minimizing a fitness function involving the temperature profiles obtained from simulated or clinical data to those obtained by the finite different scheme.