Controlling wound healing through debridement

  • Authors:
  • M. A. Jones;B. Song;D. M. Thomas

  • Affiliations:
  • -;-;-

  • Venue:
  • Mathematical and Computer Modelling: An International Journal
  • Year:
  • 2004

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Abstract

The formation of slough (dead tissue) on a wound is widely accepted as an inhibitor to natural wound healing. In this article, a system of differential equations that models slough/wound interaction is developed. We prove a threshold theorem that provides conditions on the amount of slough to guarantee wound healing. As a state-dependent time scale, debridement (the periodic removal of slough) is used as a control. We show that closure of the wound can be reached in infinite time by debriding.