Workflow handbook 1997
Simulating organizations: computational models of institutions and groups
Simulating organizations: computational models of institutions and groups
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ACM Transactions on Database Systems (TODS)
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The Knowledge Engineering Review
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AIME '01 Proceedings of the 8th Conference on AI in Medicine in Europe: Artificial Intelligence Medicine
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Temporal reasoning for decision support in medicine
Artificial Intelligence in Medicine
Artificial Intelligence in Medicine
Combining task execution and background knowledge for the verification of medical guidelines
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Data & Knowledge Engineering
An Ontology-Driven Agent-Based Clinical Guideline Execution Engine
AIME '07 Proceedings of the 11th conference on Artificial Intelligence in Medicine
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CEEMAS '07 Proceedings of the 5th international Central and Eastern European conference on Multi-Agent Systems and Applications V
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Expert Systems with Applications: An International Journal
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Computers in Biology and Medicine
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BPM'07 Proceedings of the 2007 international conference on Business process management
Methodological Review: Formal representation of eligibility criteria: A literature review
Journal of Biomedical Informatics
Journal of Biomedical Informatics
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Applied Intelligence
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AIME'11 Proceedings of the 13th conference on Artificial intelligence in medicine
Managing clinical guidelines contextualization in the GLARE system
AI*IA'05 Proceedings of the 9th conference on Advances in Artificial Intelligence
Semantic correctness in adaptive process management systems
BPM'06 Proceedings of the 4th international conference on Business Process Management
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Artificial Intelligence in Medicine
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Artificial Intelligence in Medicine
Ontology-driven execution of clinical guidelines
Computer Methods and Programs in Biomedicine
Multiple representations and multi-modal reasoning in medical diagnostic systems
Artificial Intelligence in Medicine
Flexible guideline-based patient careflow systems
Artificial Intelligence in Medicine
Customer-Centered Careflow Modeling Based on Guidelines
Journal of Medical Systems
A knowledge-based architecture for the management of patient-focused care pathways
Applied Intelligence
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This paper describes a methodology for achieving an efficient implementation of clinical practice guidelines. Three main steps are illustrated: knowledge representation, model simulation and implementation within a health care organisation. The resulting system can be classified as a 'guideline-based careflow management system'. It is based on computational formalisms representing both medical and health care organisational knowledge. This aggregation allows the implementation of a guideline, not only as a simple reminder, but also as an 'organiser' that facilitates health care processes. As a matter of fact, the system not only suggests the tasks to be performed, but also the resource allocation. The methodology initially comprehends a graphical editor, that allows an unambiguous representation of the guideline. Then the guideline is translated into a high-level Petri net. The resources, both human and technological necessary for performing guideline-based activities, are also represented by means of an organisational model. This allows the running of the Petri net for simulating the implementation of the guideline in the clinical setting. The purpose of the simulation is to validate the careflow model and to suggest the optimal resource allocation before the careflow system is installed. The final step is the careflow implementation. In this phase, we show that the 'workflow management' technology, widely used in business process automation, may be transferred to the health care setting. This requires augmenting the typical workflow management systems with the flexibility and the uncertainty management, typical of the health care processes. For illustrating the proposed methodology, we consider a guideline for the management of patients with acute ischemic stroke.