Fluid-dynamics modelling of the human left ventricle with dynamic mesh for normal and myocardial infarction: Preliminary study

Authors:
S. S. Khalafvand;E. Y. K. Ng;L. Zhong;T. K. Hung
Affiliations:
School of Mechanical and Aerospace Engineering, College of Engineering, 50 Nanyang Avenue, Nanyang Technological University, Singapore 639798, Singapore;School of Mechanical and Aerospace Engineering, College of Engineering, 50 Nanyang Avenue, Nanyang Technological University, Singapore 639798, Singapore;Department of Cardiology, National Heart Centre, Mistri Wing 17, 3rd Hospital Avenue, Singapore 168752, Singapore;Department of Bioengineering, University of Pittsburgh, Pittsburgh, PA 15261, USA
Venue:
Computers in Biology and Medicine
Year:
2012

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Abstract

Pulsating blood flow patterns in the left ventricular (LV) were computed for three normal subjects and three patients after myocardial infarction (MI). Cardiac magnetic resonance (MR) images were obtained, segmented and transformed into 25 frames of LV for a computational fluid dynamics (CFD) study. Multi-block structure meshes were generated for 25 frames and 75 intermediate grids. The complete LV cycle was modelled by using ANSYS-CFX 12. The flow patterns and pressure drops in the LV chamber of this study provided some useful information on intra-LV flow patterns with heart diseases.