Finding gene coherent patterns using PATSUB+

Authors:
H. A. Ahmed;P. Mahanta;D. K. Bhattacharyya
Affiliations:
Tezpur University, Tezpur, Assam, India;Tezpur University Tezpur, Assam, India;Tezpur University Tezpur, Assam, India
Venue:
Proceedings of the International Conference on Advances in Computing, Communications and Informatics
Year:
2012

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Abstract

This paper presents a pattern aided subspace clustering algorithm (PATSUB+) to find biologically relevant coexpressed patterns in gene expression data. The algorithm works iteratively over a relative expression domain using NMRS (Normalized Mean Residue Similarity) measure, it discovers a set of possibly overlapping subspace clusters for any gene expression matrix. PATSUB+ performs satisfactorily while tested on several real life gene expression datasets and compared with several competing algorithms.