A three-dimensional computational model of the innate immune system

Authors:
Pedro Augusto F. Rocha;Micael P. Xavier;Alexandre B. Pigozzo;Barbara de M. Quintela;Gilson C. Macedo;Rodrigo Weber dos Santos;Marcelo Lobosco
Affiliations:
Graduate Program in Computational Modelling, UFJF, Juiz de Fora, MG, Brazil;Graduate Program in Computational Modelling, UFJF, Juiz de Fora, MG, Brazil;Graduate Program in Computational Modelling, UFJF, Juiz de Fora, MG, Brazil;Graduate Program in Computational Modelling, UFJF, Juiz de Fora, MG, Brazil;Graduate Program in Biological Science, UFJF, Juiz de Fora, MG, Brazil;Graduate Program in Computational Modelling, UFJF, Juiz de Fora, MG, Brazil;Graduate Program in Computational Modelling, UFJF, Juiz de Fora, MG, Brazil
Venue:
ICCSA'12 Proceedings of the 12th international conference on Computational Science and Its Applications - Volume Part I
Year:
2012

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Abstract

The Human Immune System is a complex system responsible for protecting the organism against diseases. Although understanding how it works is essential to develop better treatments against diseases, its complexity makes this task extremely hard. In this work a three-dimensional mathematical and computational model of part of this system, the innate immune system, is presented. The high computational costs associated to simulations lead the development of a parallel version of the code, which has achieved a speedup of about 72 times over its sequential counterpart.