Multimodal neuroimaging predictors for cognitive performance using structured sparse learning
MBIA'12 Proceedings of the Second international conference on Multimodal Brain Image Analysis
On the equivalent of low-rank linear regressions and linear discriminant analysis based regressions
Proceedings of the 19th ACM SIGKDD international conference on Knowledge discovery and data mining
IPMI'13 Proceedings of the 23rd international conference on Information Processing in Medical Imaging
Exact top-k feature selection via l2,0-norm constraint
IJCAI'13 Proceedings of the Twenty-Third international joint conference on Artificial Intelligence
Adaptive loss minimization for semi-supervised elastic embedding
IJCAI'13 Proceedings of the Twenty-Third international joint conference on Artificial Intelligence
Multiple task learning using iteratively reweighted least square
IJCAI'13 Proceedings of the Twenty-Third international joint conference on Artificial Intelligence
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Alzheimer's disease (AD) is a neurodegenerative disorder characterized by progressive impairment of memory and other cognitive functions, which makes regression analysis a suitable model to study whether neuroimaging measures can help predict memory performance and track the progression of AD. Existing memory performance prediction methods via regression, however, do not take into account either the interconnected structures within imaging data or those among memory scores, which inevitably restricts their predictive capabilities. To bridge this gap, we propose a novel Sparse Multi-tAsk Regression and feaTure selection (SMART) method to jointly analyze all the imaging and clinical data under a single regression framework and with shared underlying sparse representations. Two convex regularizations are combined and used in the model to enable sparsity as well as facilitate multi-task learning. The effectiveness of the proposed method is demonstrated by both clearly improved prediction performances in all empirical test cases and a compact set of selected RAVLT-relevant MRI predictors that accord with prior studies.