Services, standards, and technologies for high performance computational proteomics

Authors:
Mario Cannataro;Pierangelo Veltri
Affiliations:
Laboratory of Bioinformatics, University Magna Græcia of Catanzaro, Catanzaro, Italy;Laboratory of Bioinformatics, University Magna Græcia of Catanzaro, Catanzaro, Italy
Venue:
ISPA'07 Proceedings of the 2007 international conference on Frontiers of High Performance Computing and Networking
Year:
2007

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Abstract

Proteomics is about the study of the proteins expressed in an organism or a cell. Computational Proteomics regards the computational methods, algorithms, databases, and methodologies used to manage, analyze and interpret the data produced in proteomics experiments. The broad application of proteomics and the increasing resolution offered by technological platforms, especially in Mass Spectrometry-based high-throughput proteomics, make the analysis of proteomics experiments difficult and error prone without efficient algorithms and easy-to-use tools. The paper discusses the requirements of Mass Spectrometrybased Computational Proteomics applications and surveys important services, standards, and technologies useful to build modular, scalable and reusable applications in this field.