Swarm optimization and Flexible Neural Tree for microarray data classification

  • Authors:
  • Aruchamy Rajini;Vasantha kalyani David

  • Affiliations:
  • Hindusthan College of Arts & Science, Coimbatore;Avinashilingam Deemed University, Coimbatore

  • Venue:
  • Proceedings of the Second International Conference on Computational Science, Engineering and Information Technology
  • Year:
  • 2012

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Abstract

Robust and accurate cancer diagnosis and classification is very important in cancer treatment. A microarray data produce a large amount of data that are irrelevant, noisy and highly dimensional. Most of the genes are uninformative which degrades the performance of data mining and machine learning tasks. To reduce the curse of dimensionality, a preprocessing step known as feature selection is done. Feature selection is referred as selecting only a fraction of features that are most predictive of a given outcome. To deal with these issues, classification tools should robustly learn to identify a subset of informative genes embedded in large data set that has high dimensional noises. In this paper, an integrated approach of FNT (Flexible Neural Tree) and swarm optimization is proposed to simultaneously optimize the selection of feature subset and the classifier. A hierarchical neural network like structure is flexible neural tree (FNT).which is automatically created and optimized using evolutionary like algorithms to solve a given problem. Because of the most distinctive feature of flexible neural tree structure, it is not necessary to set the structure and weights of neural networks prior the problem is solved. The architecture of FNT is created with Ant Colony Optimization (ACO) and the parameters of the neural tree are optimized by Particle Swarm Optimization (PSO) algorithm and its enhancement (EPSO). The experimental results indicate that the proposed technique is feasible and efficient for the classification of microarray data.