Feature extraction for mass spectrometry data

  • Authors:
  • Yihui Liu

  • Affiliations:
  • School of Computer Science and Information Technology, Shandong Institute of Light Industry, Jinan, Shandong, China

  • Venue:
  • LSMS'07 Proceedings of the 2007 international conference on Life System Modeling and Simulation
  • Year:
  • 2007

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Abstract

Mass spectrometry is being used to generate protein profiles from human serum, and proteomic data obtained from mass spectrometry have attracted great interest for the detection of early-stage cancer. However, high dimensional mass spectrometry data cause considerable challenges. In this paper a set of wavelet detail coefficients at different levels is used to characterize the localized changes of mass spectrometry data and reduce dimensionality of mass spectra. The experiments are performed on high resolution ovarian dataset. A highly competitive accuracy compared to the best performance of other kinds of classification models is achieved.