Texture feature ranking with relevance learning to classify interstitial lung disease patterns

  • Authors:
  • Markus B. Huber;Kerstin Bunte;Mahesh B. Nagarajan;Michael Biehl;Lawrence A. Ray;Axel WismüLler

  • Affiliations:
  • Departments of Imaging Sciences and Biomedical Engineering, University of Rochester, NY, United States;Johann Bernoulli Institute for Mathematics and Computer Science, University of Groningen, The Netherlands;Departments of Imaging Sciences and Biomedical Engineering, University of Rochester, NY, United States;Johann Bernoulli Institute for Mathematics and Computer Science, University of Groningen, The Netherlands;Research Laboratories, Carestream Health, Inc., NY, United States;Departments of Imaging Sciences and Biomedical Engineering, University of Rochester, NY, United States and Department of Radiology, Ludwig Maximilians University, Munich, Germany

  • Venue:
  • Artificial Intelligence in Medicine
  • Year:
  • 2012

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Abstract

Objective: The generalized matrix learning vector quantization (GMLVQ) is used to estimate the relevance of texture features in their ability to classify interstitial lung disease patterns in high-resolution computed tomography images. Methodology: After a stochastic gradient descent, the GMLVQ algorithm provides a discriminative distance measure of relevance factors, which can account for pairwise correlations between different texture features and their importance for the classification of healthy and diseased patterns. 65 texture features were extracted from gray-level co-occurrence matrices (GLCMs). These features were ranked and selected according to their relevance obtained by GMLVQ and, for comparison, to a mutual information (MI) criteria. The classification performance for different feature subsets was calculated for a k-nearest-neighbor (kNN) and a random forests classifier (RanForest), and support vector machines with a linear and a radial basis function kernel (SVMlin and SVMrbf). Results: For all classifiers, feature sets selected by the relevance ranking assessed by GMLVQ had a significantly better classification performance (p