A tutorial on spectral clustering
Statistics and Computing
ISBI'10 Proceedings of the 2010 IEEE international conference on Biomedical imaging: from nano to Macro
Heterogeneous image feature integration via multi-modal spectral clustering
CVPR '11 Proceedings of the 2011 IEEE Conference on Computer Vision and Pattern Recognition
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In-vivo parcellation of the cerebral cortex via non-invasive neuroimaging data has been in active research for years. A variety of model-driven and/or data-driven computational approaches have been proposed to parcellate the cortex. However, two fundamental common issues in these parcellation methodologies are the features or attributes used to define boundaries between cortical regions and the establishment of correspondences of the parcellated regions across different brains. This paper uses a novel DTI-derived fiber shape feature for the parcellation of cortical gyrus into fine-granularity segments. The gyral parcellation is formulated and solved as a surface vertex clustering problem, in which fiber shape feature similarity is used to define the distances between vertices. Then, we designed and applied a novel multi-view spectral clustering algorithm to group the vertices into group-wise consistent gyral segments across different brains. The experimental results showed that the precentral and postcentral gyrus, as two test-beds, can be consistently parcellated into 10 segments on both hemispheres across different subjects. Evaluation studies using benchmark task-based fMRI and cortical landmarks demonstrated the effectiveness and validity of the proposed methods.