Hemodynamic assessment of pre- and post-operative aortic coarctation from MRI

Authors:
Kristóf Ralovich;Lucian Itu;Viorel Mihalef;Puneet Sharma;Razvan Ionasec;Dime Vitanovski;Waldemar Krawtschuk;Allen Everett;Richard Ringel;Nassir Navab;Dorin Comaniciu
Affiliations:
Technical University of Munich, Germany, Siemens Corporation, Corporate Research and Technology;Siemens Corporation, Corporate Research and Technology, USA, Transilvania University of Brasov, Romania;Siemens Corporation, Corporate Research and Technology;Siemens Corporation, Corporate Research and Technology;Siemens Corporation, Corporate Research and Technology;Siemens Corporation, Corporate Research and Technology, USA, Friedrich-Alexander University Erlangen-Nuremberg, Germany;Siemens Corporation, Corporate Research and Technology, USA, Friedrich-Alexander University Erlangen-Nuremberg, Germany;The Johns Hopkins Hospital;The Johns Hopkins Hospital;Technical University of Munich, Germany;Siemens Corporation, Corporate Research and Technology
Venue:
MICCAI'12 Proceedings of the 15th international conference on Medical Image Computing and Computer-Assisted Intervention - Volume Part II
Year:
2012

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Abstract

Coarctation of the aorta (CoA), is a congenital defect characterized by a severe narrowing of the aorta, usually distal to the aortic arch. The treatment options include surgical repair, stent implantation, and balloon angioplasty. In order to evaluate the physiological significance of the pre-operative coarctation and to assess the post-operative results, the hemodynamic analysis is usually performed by measuring the pressure gradient ($\triangle P$) across the coarctation site via invasive cardiac catheterization. The measure of success is reduction of the ($\triangle P 20 mmHg$) systolic blood pressure gradient. In this paper, we propose a non-invasive method based on Computational Fluid Dynamics and MR imaging to estimate the pre- and post-operative hemodynamics for both native and recurrent coarctation patients. High correlation of our results and catheter measurements is shown on corresponding pre- and post-operative examination of 5 CoA patients.