Characterizing Correctness Properties of Parallel Programs Using Fixpoints
Proceedings of the 7th Colloquium on Automata, Languages and Programming
Model Checking Performability Properties
DSN '02 Proceedings of the 2002 International Conference on Dependable Systems and Networks
Model-Checking Algorithms for Continuous-Time Markov Chains
IEEE Transactions on Software Engineering
SGN Sim, a Stochastic Genetic Networks Simulator
Bioinformatics
Probabilistic model checking of complex biological pathways
Theoretical Computer Science
Model Checking Timed and Stochastic Properties with CSL^{TA}
IEEE Transactions on Software Engineering
Quantitative Model Checking of Continuous-Time Markov Chains Against Timed Automata Specifications
LICS '09 Proceedings of the 2009 24th Annual IEEE Symposium on Logic In Computer Science
A Bayesian Approach to Model Checking Biological Systems
CMSB '09 Proceedings of the 7th International Conference on Computational Methods in Systems Biology
Query-based verification of qualitative trends and oscillations in biochemical systems
Theoretical Computer Science
SFM'07 Proceedings of the 7th international conference on Formal methods for performance evaluation
Formal cell biology in biocham
SFM'08 Proceedings of the Formal methods for the design of computer, communication, and software systems 8th international conference on Formal methods for computational systems biology
MARCIE - Model Checking and Reachability Analysis Done EffiCIEntly
QEST '11 Proceedings of the 2011 Eighth International Conference on Quantitative Evaluation of SysTems
COSMOS: A Statistical Model Checker for the Hybrid Automata Stochastic Logic
QEST '11 Proceedings of the 2011 Eighth International Conference on Quantitative Evaluation of SysTems
HASL: an expressive language for statistical verification of stochastic models
Proceedings of the 5th International ICST Conference on Performance Evaluation Methodologies and Tools
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The recently introduced Hybrid Automata Stochastic Logic (HASL) establishes a powerful framework for the analysis of a broad class of stochastic processes, namely Discrete Event Stochastic Processes (DESPs). Here we demonstrate the potential of HASL based verification in the context of genetic circuits. To this aim we consider the analysis of a model of gene expression with delayed stochastic dynamics, a class of systems whose dynamics includes both Markovian and non-Markovian events. We identify a number of relevant properties related to this model, formally express them in HASL terms and, assess them with COSMOS, a statistical model checker for HASL model checking. We demonstrate that this allows assessing the "performances" of a biological system beyond the capability of other stochastic logics.