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A mobile e-Health information system MEHIS aims to speed up the operations of health care in medical centers and hospitals. However, the proper implementation of MEHIS involves integrating many subsystems for MEHIS to be properly executed. A typical MEHIS can consist of many components and subsystems, such as appointments and scheduling; admission, discharge, and transfer ADT; prescription order entry; dietary planning; and smart card sign-on. This paper describes the development of a MEHIS with open-source Eclipse, using currently available health care standards. The author discusses the issues of building a mobile e-Health information system which can help achieve the goal of ubiquitous and mobile applications for the personalization of e-Health.