Histogram Analysis Using a Scale-Space Approach
IEEE Transactions on Pattern Analysis and Machine Intelligence
Improvement of Kittler and Illingworth's minimum error thresholding
Pattern Recognition
Binarization and multithresholding of document images using connectivity
CVGIP: Graphical Models and Image Processing
A fast thresholding selection procedure for multimodal and unimodal histograms
Pattern Recognition Letters
Automatic threshold selection based on histogram modes and a discriminant criterion
Machine Vision and Applications
Image Thresholding by Indicator Kriging
IEEE Transactions on Pattern Analysis and Machine Intelligence
A novel fuzzy entropy approach to image enhancement and thresholding
Signal Processing
Operations Useful for Similarity-Invariant Pattern Recognition
Journal of the ACM (JACM)
Quantitative fuzzy measures for threshold selection
Pattern Recognition Letters
Vessel Extractio Techniques and Algorithms: A Survey
BIBE '03 Proceedings of the 3rd IEEE Symposium on BioInformatics and BioEngineering
A review of vessel extraction techniques and algorithms
ACM Computing Surveys (CSUR)
A multistage adaptive thresholding method
Pattern Recognition Letters
A multi-level thresholding approach using a hybrid optimal estimation algorithm
Pattern Recognition Letters
A double-threshold image binarization method based on edge detector
Pattern Recognition
MICCAI '08 Proceedings of the 11th international conference on Medical Image Computing and Computer-Assisted Intervention - Part I
Accurate segmentation of dermoscopic images by image thresholding based on type-2 fuzzy logic
IEEE Transactions on Fuzzy Systems
Digital image thresholding, based on topological stable-state
Pattern Recognition
Directional histogram model for three-dimensional shape similarity
CVPR'03 Proceedings of the 2003 IEEE computer society conference on Computer vision and pattern recognition
Median-based image thresholding
Image and Vision Computing
IEEE Transactions on Pattern Analysis and Machine Intelligence
Threshold Selection Using Quadtrees
IEEE Transactions on Pattern Analysis and Machine Intelligence
Computer-Supported Angiogenesis Quantification Using Image Analysis and Statistical Averaging
IEEE Transactions on Information Technology in Biomedicine
A new criterion for automatic multilevel thresholding
IEEE Transactions on Image Processing
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With the development of micron-scale imaging techniques, capillaries can be conveniently visualized using methods such as two-photon and whole mount microscopy. However, the presence of background staining, leaky vessels and the diffusion of small fluorescent molecules can lead to significant complexity in image analysis and loss of information necessary to accurately quantify vascular metrics. One solution to this problem is the development of accurate thresholding algorithms that reliably distinguish blood vessels from surrounding tissue. Although various thresholding algorithms have been proposed, our results suggest that without appropriate pre- or post-processing, the existing approaches may fail to obtain satisfactory results for capillary images that include areas of contamination. In this study, we propose a novel local thresholding algorithm, called directional histogram ratio at random probes (DHR-RP). This method explicitly considers the geometric features of tube-like objects in conducting image binarization, and has a reliable performance in distinguishing small vessels from either clean or contaminated background. Experimental and simulation studies suggest that our DHR-RP algorithm is superior over existing thresholding methods.