Design and implementation of the GLIF3 guideline execution engine
Journal of Biomedical Informatics
Journal of Biomedical Informatics
Artificial Intelligence in Medicine
Argumentation-Based Inference and Decision Making--A Medical Perspective
IEEE Intelligent Systems
Computer Methods and Programs in Biomedicine
Journal of Biomedical Informatics
Journal of Biomedical Informatics
A framework for distributed mediation of temporal-abstraction queries to clinical databases
Artificial Intelligence in Medicine
A goal-oriented framework for specifying clinical guidelines and handling medical errors
Journal of Biomedical Informatics
Agent-based execution of personalised home care treatments
Applied Intelligence
Artificial Intelligence in Medicine
Ontology-driven execution of clinical guidelines
Computer Methods and Programs in Biomedicine
KR4HC'11 Proceedings of the 3rd international conference on Knowledge Representation for Health-Care
BPM' 2012 Proceedings of the 2012 international conference on Process Support and Knowledge Representation in Health Care
A knowledge-based architecture for the management of patient-focused care pathways
Applied Intelligence
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Clinicians can benefit from automated support to guideline (GL) application at the point of care. However, several conceptual dimensions should be considered for a realistic application: 1) The representation of the knowledge might be through structured text (semi-formal), or specified in a machine-comprehensible language (formal); 2) The availability of electronic patient data might be partial or full; 3) GL-based recommendations might be triggered by a human-initiated (synchronous) session, or data---driven (asynchronous). In addition, several requirements must be fulfilled, such as an evaluation of the GL application engine by a GL simulation engine. Finally, to apply multiple GLs, by multiple users, in multiple settings, the GL-application engine should be designed as an enterprise architecture that can plug into any Electronic Medical Record (EMR). We present an architecture fulfilling these desiderata, describe application examples with different conceptual dimensions and requirements, using our new GL-application engine, PICARD, discuss lessons learned, and briefly describe a clinical evaluation of the current framework in the domain of pre-eclampsia/toxemia of pregnancy.