Novel vector-valued approach to automatic brain tissue classification

  • Authors:
  • Nataliya Portman;Alan Evans

  • Affiliations:
  • McConnell Brain Imaging Centre, Montreal Neurological Institute, Montreal, Quebec, Canada;McConnell Brain Imaging Centre, Montreal Neurological Institute, Montreal, Quebec, Canada

  • Venue:
  • MCV'12 Proceedings of the Second international conference on Medical Computer Vision: recognition techniques and applications in medical imaging
  • Year:
  • 2012

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Abstract

In this work we propose a novel SSIM (Structural Similarity Index Measure)-guided brain tissue classification approach, implementing Kernel Fisher Discriminant Analysis (KFDA). In Computer Vision, KFDA has been shown to be competitive with other state-of-the-art techniques. In the KFDA-based framework, we exploit the complex structure of grey matter, white matter and cerebro-spinal fluid intensity clusters to find an optimal classification. We illustrate our novel technique using a dataset of early normal brain development in the age range from 10 days to 4.5 years. The SSIM metric, an objective measure of an image quality as perceived by the Human Visual System, is used to evaluate the quality of brain segmentation. SSIM comparison of the quality of classification obtained by the KFDA-based and the Expectation-Maximization algorithms shows the superior performance of the proposed technique.