Variational Methods for Multimodal Image Matching
International Journal of Computer Vision
Serial nonrigid vascular registration using weighted normalized mutual information
ISBI'10 Proceedings of the 2010 IEEE international conference on Biomedical imaging: from nano to Macro
System to guide transcatheter aortic valve implantations based on interventional c-arm CT imaging
MICCAI'10 Proceedings of the 13th international conference on Medical image computing and computer-assisted intervention: Part I
Model-based fusion of multi-modal volumetric images: application to transcatheter valve procedures
MICCAI'11 Proceedings of the 14th international conference on Medical image computing and computer-assisted intervention - Volume Part I
IPMI'05 Proceedings of the 19th international conference on Information Processing in Medical Imaging
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Trans-catheter Aortic Valve Implantation (TAVI) has proven to be an effective minimal-invasive alternative to traditional open-heart valve replacement surgery. Despite the success of contrast enhanced C-arm CT for intra-operative guidance during TAVI, utilization of pre-operative CT in the Hybrid Operating Room provides additional advantages of an improved workflow and minimized usage of contrast agent. In this paper, we propose a framework for CT/non-contrast-enhanced C-arm CT volume registration so that pre-operative CT can be used intra-operatively without additional contrast medium. The proposed method consists of two steps, rigid-body coarse alignment followed by deformable fine registration. Our contribution is twofold. First, robust heart center detection on both image modalities is used to boost the success rate of rigid-body registration. Second, a structural encoded similarity measure and anatomical correlation-regularized deformation fields are proposed to improve the performance of intensity-based deformable registration using the variational framework. Experiments were performed on ten sets of TAVI patient data, and the results have shown that the proposed method provides a highly robust and accurate registration. The resulting accuracy of 1.83 mm mean mesh-to-mesh error at the aortic root and the high efficiency of an average running time of 2 minutes on a common computer make it potentially feasible for clinical usage in TAVI. The proposed heart registration method is generic and hence can be easily applied to other cardiac applications.